CSV Bulk calculations specifications: ALL
This type of CSV allows all adjustments at once for each row.
Input Variables
A CSV input file should always have 26 columns.
An optional header can be sent as first line of the CSV file:
Score unit,Country,Age,Sex,BMI,Previous fracture,Parental history,Current smoker,Gluccocorticoid,Rheumatoid Arthritis,Secondary osteoporosis,Alcohol,Femoral neck BMD,PREV/VERT time,PREV/HIP time,PREV/HUM time,PREV/FA time,PREV/OOP time,COR dose,TBS value,TBS scanning equipment,DIA duration,FALL number falls,FNLS t-score,HAL,PHPT without PTX,Number of Previous Fracture
The first columns are the FRAX variables:
| # | Col | Variable | Description | Possible Values |
|---|---|---|---|---|
| 1 | A | Score unit | Unit for variable 13 | t: T-score, z: Z-score. Unit for parameter 13 (BMD) described below. |
| 2 | B | Country | Code for country and ethnicity | Integer. Get valid countries' id from the API. |
| 3 | C | Age | Age in years | Positive real number (40-90), can have decimals. Out of bound values will be capped. |
| 4 | D | Sex | Gender | 0: men, 1: women |
| 5 | E | BMI | Body Mass Index | Positive real number (kg/m²), can have decimals |
| 6 | F | Previous fracture | History of previous fracture | 0: no, 1: yes |
| 7 | G | Parental history | Parent(s) with hip fracture history | 0: no, 1: yes |
| 8 | H | Current smoker | Current smoking status | 0: no, 1: yes |
| 9 | I | Gluccocorticoid | Gluccocorticoid use | 0: no, 1: yes |
| 10 | J | Rheumatoid Arthritis | Presence of rheumatoid arthritis | 0: no, 1: yes |
| 11 | K | Secondary osteoporosis | Presence of secondary osteoporosis | 0: no, 1: yes |
| 12 | L | Alcohol | More than two drinks a day | 0: no, 1: yes |
| 13 | M | Femoral neck BMD | Bone mineral density measurement | Real number (T-score or Z-score). The T-score for both genders should be derived by comparing the individual BMD to the young normal FEMALE NHANES III reference range for the make of scanner that you are using. |
Then we need the adjustments variables:
| # | Col | Variable | Description | Possible Values |
|---|---|---|---|---|
| 14 | N | PREV/VERT time | Period since vertebral fracture | 0-1M, 1-6M, 6-12M, or 12-24M |
| 15 | O | PREV/HIP time | Period since hip fracture | 0-1M, 1-6M, 6-12M, or 12-24M |
| 16 | P | PREV/HUM time | Period since humerus fracture | 0-1M, 1-6M, 6-12M, or 12-24M |
| 17 | Q | PREV/FA time | Period since forearm fracture | 0-1M, 1-6M, 6-12M, or 12-24M |
| 18 | R | PREV/OOP time | Period since other osteoporotic fracture | 0-1M, 1-6M, 6-12M, or 12-24M |
| 19 | S | COR dose | Corticosteroid dosage | LOW (<2.5 mg/day), HIG (≥7.5 mg/day) |
| 20 | T | TBS value | Trabecular Bone Score | Real number |
| 21 | U | TBS scanning equipment | TBS measurement device | HOL, LUN |
| 22 | V | DIA duration | Time with type 2 diabetes | <5y, 5-10y, or >10y |
| 23 | W | FALL number falls | Self-reported falls in previous year | 1, 2, or 3+ |
| 24 | X | FNLS t-score | Lumbar spine T-score | Real number |
| 25 | Y | HAL | Hip axis measurement | Real number (mm) |
| 26 | Z | PHPT without PTX | Individual without parathyroidectomy (PTX) | 0 Individual without Primary Hyperparathyroidism (PHPT) or individual with PHPT but with parathyroidectomy (PTX): adjustment not possible,1 Individual with PHPT but without PTX |
| 27 | AA | Number of Previous Fracture | Number of prior fractures. | 1, 2, 3, or 4+ |
Output Results
Once processed, you will receive an output file with, for each row, the results append to the original line (the variables above).
| # | Col | Result | Description |
|---|---|---|---|
| 28 | AB | FRAX MOF wo BMD | Original major osteoporotic fracture risk without BMD |
| 29 | AC | FRAX Hip wo BMD | Original hip fracture risk without BMD |
| 30 | AD | FRAX MOF w BMD | Original major osteoporotic fracture risk with BMD |
| 31 | AE | FRAX HIP w BMD | Original hip fracture risk with BMD |
| 32 | AF | PREV/VERT MOF wo BMD | Adjusted MOF without BMD according to site and time since previous vertebral fracture |
| 33 | AG | PREV/VERT Hip wo BMD | Adjusted HIP without BMD according to site and time since previous vertebral fracture |
| 34 | AH | PREV/VERT MOF w BMD | Adjusted MOF with BMD according to site and time since previous vertebral fracture |
| 35 | AI | PREV/VERT Hip w BMD | Adjusted HIP with BMD according to site and time since previous vertebral fracture |
| 36 | AJ | PREV/HIP MOF wo BMD | Adjusted MOF without BMD according to site and time since previous hip fracture |
| 37 | AK | PREV/HIP Hip wo BMD | Adjusted HIP without BMD according to site and time since previous hip fracture |
| 38 | AL | PREV/HIP MOF w BMD | Adjusted MOF with BMD according to site and time since previous hip fracture |
| 39 | AM | PREV/HIP Hip w BMD | Adjusted HIP with BMD according to site and time since previous hip fracture |
| 40 | AN | PREV/HUM MOF wo BMD | Adjusted MOF without BMD according to site and time since previous humerus fracture |
| 41 | AO | PREV/HUM Hip wo BMD | Adjusted HIP without BMD according to site and time since previous humerus fracture |
| 42 | AP | PREV/HUM MOF w BMD | Adjusted MOF with BMD according to site and time since previous humerus fracture |
| 43 | AQ | PREV/HUM Hip w BMD | Adjusted HIP with BMD according to site and time since previous humerus fracture |
| 44 | AR | PREV/FA MOF wo BMD | Adjusted MOF without BMD according to site and time since previous forearm fracture |
| 45 | AS | PREV/FA Hip wo BMD | Adjusted HIP without BMD according to site and time since previous forearm fracture |
| 46 | AT | PREV/FA MOF w BMD | Adjusted MOF with BMD according to site and time since previous forearm fracture |
| 47 | AU | PREV/FA Hip w BMD | Adjusted HIP with BMD according to site and time since previous forearm fracture |
| 48 | AV | PREV/OOP MOF wo BMD | Adjusted MOF without BMD according to site and time since previous other osteoporotic fracture |
| 49 | AW | PREV/OOP Hip wo BMD | Adjusted HIP without BMD according to site and time since previous other osteoporotic fracture |
| 50 | AX | PREV/OOP MOF w BMD | Adjusted MOF with BMD according to site and time since previous other osteoporotic fracture |
| 51 | AY | PREV/OOP Hip w BMD | Adjusted HIP with BMD according to site and time since previous other osteoporotic fracture |
| 52 | AZ | COR MOF wo BMD | Adjusted MOF without BMD according to dose of corticosteroid |
| 53 | BA | COR Hip wo BMD | Adjusted HIP without BMD according to dose of corticosteroid |
| 54 | BB | COR MOF w BMD | Adjusted MOF with BMD according to dose of corticosteroid |
| 55 | BC | COR Hip w BMD | Adjusted HIP with BMD according to dose of corticosteroid |
| 56 | BD | TBS MOF w BMD | Adjusted MOF with BMD according to TBS value and machine |
| 57 | BE | TBS Hip w BMD | Adjusted HIP with BMD according to TBS value and machine |
| 58 | BF | DIA MOF wo BMD | Adjusted MOF without BMD according to duration of diabetes |
| 59 | BG | DIA Hip wo BMD | Adjusted HIP without BMD according to duration of diabetes |
| 60 | BH | DIA MOF w BMD | Adjusted MOF with BMD according to duration of diabetes |
| 61 | BI | DIA Hip w BMD | Adjusted HIP with BMD according to duration of diabetes |
| 62 | BJ | FALL MOF wo BMD | Adjusted MOF without BMD according to number of falls |
| 63 | BK | FALL Hip wo BMD | Adjusted HIP without BMD according to number of falls |
| 64 | BL | FALL MOF w BMD | Adjusted MOF with BMD according to number of falls |
| 65 | BM | FALL Hip w BMD | Adjusted HIP with BMD according to number of falls |
| 66 | BN | FNLS MOF w BMD | Adjusted MOF with BMD based on FN-LS discordance |
| 67 | BO | FNLS Hip w BMD | Adjusted HIP with BMD based on FN-LS discordance |
| 68 | BP | HAL MOF w BMD | Adjusted MOF with BMD according to hip axis length |
| 69 | BQ | HAL Hip w BMD | Adjusted HIP with BMD according to hip axis length |
| 70 | BR | PHPT MOF wo BMD | Adjusted MOF without BMD according to age and sex |
| 71 | BS | PHPT Hip wo BMD | Adjusted HIP without BMD according to age and sex |
| 72 | BT | PHPT MOF w BMD | Adjusted MOF with BMD according to age and sex |
| 73 | BU | PHPT Hip w BMD | Adjusted HIP with BMD according to age and sex |
| 74 | BV | NPF MOF wo BMD | Adjusted MOF without BMD according to the number of prior fractures |
| 75 | BW | NPF Hip wo BMD | Adjusted HIP without BMD according to the number of prior fractures |
| 76 | BX | NPF MOF w BMD | Adjusted MOF with BMD according to the number of prior fractures |
| 77 | BY | NPF Hip w BMD | Adjusted HIP with BMD according to the number of prior fractures |
Output warning or error reporting
If an error for any adjustments of the row has been triggered, a specific message will be added at the end of the line.
| # | Col | Processor messages |
|---|---|---|
| 78 | BZ | Warning or error messages |